The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology.
نویسندگان
چکیده
منابع مشابه
Purification and partial characterization of isoforms of luteinizing hormone from the chicken pituitary gland.
Isoforms of chicken luteinizing hormone (cLH) were isolated from chicken pituitaries by differential extraction, sequential chromatography on HPLC cation- and anion-exchange columns, and gel-filtration chromatography. Three purified isoforms of the cLH had high biological potency in the chicken granulosa cell LH bioassay (4.21-7.4 x NIH-LH-S1 U/mg). One cLH isoform without detectable biological...
متن کاملCloning and expression of Iranian Turkmen-thoroughbred horse follicle stimulating hormone in Pichia pastoris
Background: Follicle stimulating hormone (FSH) plays an essential role in reproductive physiology and follicular development. Objective: A new variant of the equine fsh (efsh) gene was cloned, sequenced, and expressed in Pichia pastoris (P. pastoris) GS115 yeast expression system. Materials and Methods: The full-length cDNAs of the efshα and efshβ chains were amplified by reverse transcriptio...
متن کاملPurification and characterization of chicken follicle-stimulating hormone.
1. Highly purified chicken follicle-stimulating hormone (cFSH) was isolated from chicken pituitaries by differential extraction, sequential chromatography on HPLC cation and anion exchange columns, and gel filtration chromatography. 2. Purified cFSH (USDA-cFSH-K-1) had a potency of 77.44 units/mg in a chicken testes radioreceptor assay, and was biologically active in stimulating the secretion o...
متن کاملProtective effect of vitamin D on Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), testosterone hormones and testicular tissue changes induced by methotrexate in adult male rats
Background and Aims: Vitamin D has antioxidant and anti-inflammatory activities. The present study aimed to investigate the protective effect of vitamin D on Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), testosterone hormones and testicular tissue changes induced by methotrexate in adult male rats. Materials and Methods: In this experimental study, 30 adult male Wistar rats wei...
متن کاملMutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.
The recent unraveling of structures of genes for the gonadotropin subunits and gonadotropin receptors has provided reproductive endocrinologists with new tools to study normal and pathological functions of the hypothalamic-pituitary-gonadal axis. Rare inactivating mutations that produce distinctive phenotypes of isolated LH or FSH deficiency have been discovered in gonadotropin subunit genes. I...
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ورودعنوان ژورنال:
- Endocrine reviews
دوره 18 6 شماره
صفحات -
تاریخ انتشار 1997